Near Infrared Light Heating of Soft Tissue Phantoms Containing Nanoparticles

Simon Eibner (1) , Rodrigo A. O. Jaime (2) , Bernard Lamien (2) , Rodrigo L. Q. Basto (2) , Helcio Rangel Barreto Orlande (2) , Olivier Fudym (1)

1 RAPSODEE - Centre de recherche d'Albi en génie des procédés des solides divisés, de l'énergie et de l'environnement
2 UFRJ - Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil]

The objective of this paper is to investigate the effect of the addition of nanoparticles to soft tissue phantoms, aiming at the enhancement of photothermal therapy for cancer. The phantoms were made of Polyvinyl chloride-plastisol (PVC-P), with two different nanoparticles, namely, titanium dioxide nanoparticles (TiO2) and silica nanoparticles (SiO2). A phantom without nanoparticles and a phantom containing a thermal paste were also manufactured for comparison purposes. The PVC-P phantom is transparent to the near infrared laser light, whereas the addition of titanium dioxide nanoparticles modified the optical properties enhancing the local heating, as demonstrated through experiments with a laser-diode and an infrared camera.

Mots clés: hyperthermia; NIR laser; Photothermal therapy; Phantom; Photoabsorbing nanoparticles

Domaines: Sciences de l'ingénieur [physics]

Simon Eibner, Rodrigo A. O. Jaime, Bernard Lamien, Rodrigo L. Q. Basto, Helcio Rangel Barreto Orlande, et al.. Near Infrared Light Heating of Soft Tissue Phantoms Containing Nanoparticles. ENCIT 2012 - 14th Brazilian Congress of Thermal Sciences and Engineering, Nov 2012, Rio de Janeiro, Brazil. ⟨hal-02086617⟩