Lipid nanoparticles as carriers for cosmetic ingredients : the first (SLN) and the second generation (NLC)

Kleber Guimaraes (1) , Maria-Inês Ré (2)

1 São Paulo State Institute for Technological Research
2 RAPSODEE - Centre de recherche d'Albi en génie des procédés des solides divisés, de l'énergie et de l'environnement

Colloidal carrier systems like solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were developed with a perspective to meet industrial needs related to a simple technology involving low costs and easiness for scaling-up ensuring the process qualification and validation required for the pharmaceutical and cosmetic industries. Production methods which are suitable for large scale production, innovative applications, recent advances and technological challenges are some of the aspects which are outlined in this chapter. Appropriate analytical techniques suitable for characterizing SLN and NLC are also discussed because of their relevance for product development.

Mots clés: Cholesterol; Crystallization; Hydration; Enthalpy; Dexamethasone

Domaines: Sciences de l'ingénieur [physics]

Kleber Guimaraes, Maria-Inês Ré. Lipid nanoparticles as carriers for cosmetic ingredients : the first (SLN) and the second generation (NLC). Extrait de : Nanocosmetics and nanomedicines - new approaches for skin care (chap.5) / sous la dir. de R. BECK, S. GUTERRES et A.POHLMANN , Springer, p.101-122, 2011, 978-3-642-19791-8. ⟨10.1007/978-3-642-19792-5_5⟩. ⟨hal-01729154⟩